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Real World Success

Internationally several countries have initiated HPV Vaccination Programmes, amongst these are: Australia, New Zealand, Sweden, Belgium, the United States, Brazil, Denmark and many more.42, 43, 44, 45, 46, 47, 48

  • Surveillance studies in multiple countries including Australia, New Zealand, Sweden, Germany, Belgium and the United States have consistently demonstrated the rapid real world impact on HPV infection and disease resulting from vaccination with the quadrivalent Human Papillomavirus (qHPV) vaccine.8, 42, 43, 44, 45, 46, 47, 48
  • Significant declines have been seen in the incidence of genital wart diagnoses following a vaccination programme with the quadrivalent HPV vaccine.19, 40
    • The incidents of genital warts among young adult females in surveillance studies in Australia is now nearly 0 %.
  • Significant reductions in high-grade cervical abnormalities among young adult females have also been observed.21
    • In Australia, a decline in incidence of CIN2+ lesions has been observed among females <18 years of age.21
    • In the United States, a reduction in HPV 16/18-related CIN 2/3 among vaccinated young adult females has been reported.8
  • After 4 years of a vaccination programme in Australia, a substantial decrease in the prevalence of vaccine HPV type infections is evident.19, 40
  • This is the 1st evidence of the protective impact of HPV vaccination against prevalence of HPV type-specific infection outside of clinical trials.19, 40